Image:Enzyme cascade.jpg

Figure 1: Diagram illustrating the enzyme cascade that occurs when hormones(and neural signals)catalyze the activation of phosphorylase through kinase activity and thus inactivating glycogen synthetase. Phosphatases inactivate phosphorylase and is regulated by phosphorylase itself as well as inhibitor proteins. High glucose concentratios also lead to the inactivation of phosphorylase (inactivation represented by open arrows). Diagram adapted from (Ref).